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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
Search by
Maps
Select Remote Interfaces
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SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository
Exclude local DBs
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Searching in 'USC-OGP 2-DE database' for entry
matching:
P42574
USC-OGP 2-DE database
:
P42574
P42574
General information about the entry
View entry in simple text format
Entry name
CASP3_HUMAN
Primary accession number
P42574
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Caspase-3; Short=CASP-3; EC=3.4.22.56; AltName: Full=Apopain; AltName: Full=Cysteine protease CPP32; Short=CPP-32; AltName: Full=Protein Yama; AltName: Full=SREBP cleavage activity 1; Short=SCA-1; Contains: RecName: Full=Caspase-3 subunit p17; Contains: RecName: Full=Caspase-3 subunit p12; Flags: Precursor;.
Gene name
Name=CASP3
Synonyms=CPP32
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0469
:
pI=6.04; Mw=31889
PLATELET_6-11
{PLATELET 6-11}
Homo sapiens (Human)
map experimental info
PLATELET_6-11
MAP LOCATIONS:
SPOT OGP-0985
:
pI=6.04; Mw=28989
SPOT OGP-0987
:
pI=5.85; Mw=28842
Cross-references
UniProtKB/Swiss-Prot
P42574; CASP3_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
CASP3_HUMAN
Primary accession number
P42574
Secondary accession number(s)
A8K5M2 D3DP53 Q96AN1 Q96KP2
Sequence was last modified on
October 11, 2005 (version 2)
Annotations were last modified on
March 15, 2017 (version 202)
Name and origin of the protein
Description
RecName: Full=Caspase-3; Short=CASP-3; EC=3.4.22.56; AltName: Full=Apopain; AltName: Full=Cysteine protease CPP32; Short=CPP-32; AltName: Full=Protein Yama; AltName: Full=SREBP cleavage activity 1; Short=SCA-1; Contains: RecName: Full=Caspase-3 subunit p17; Contains: RecName: Full=Caspase-3 subunit p12; Flags: Precursor;
Gene name
Name=CASP3
Synonyms=CPP32
Encoded on
Name=CASP3; Synonyms=CPP32
Keywords
3D-structure
;
Acetylation
;
Apoptosis
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Hydrolase
;
Phosphoprotein
;
Polymorphism
;
Protease
;
Reference proteome
;
S-nitrosylation
;
Thiol protease
;
Zymogen
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
U13737; AAA65015.1
; -; mRNA
EMBL
U13738; AAB60355.1
; -; mRNA
EMBL
U26943; AAA74929.1
; -; mRNA
EMBL
AJ413269; CAC88866.1
; -; mRNA
EMBL
AK291337; BAF84026.1
; -; mRNA
EMBL
AY219866; AAO25654.1
; -; Genomic_DNA
EMBL
CH471056; EAX04673.1
; -; Genomic_DNA
EMBL
CH471056; EAX04674.1
; -; Genomic_DNA
EMBL
CH471056; EAX04675.1
; -; Genomic_DNA
EMBL
BC016926; AAH16926.1
; -; mRNA
CCDS
CCDS3836.1; -
; .
PIR
A55315; A55315
; .
RefSeq
NP_004337.2; NM_004346.3
; .
RefSeq
NP_116786.1; NM_032991.2
; .
RefSeq
XP_011530603.1; XM_011532301.1
; .
UniGene
Hs.141125; -
; .
PDB
1CP3; X-ray
; 2.30 A; A/B=1-277
PDB
1GFW; X-ray
; 2.80 A; A=29-175
B=181-277
PDB; 1I3O; X-ray; 2.70 A
A/C=1-175
B/D=176-277; PDB; 1NME; X-ray
1.60 A
A=29-174; B=186-277; PDB; 1NMQ
X-ray
2.40 A; A/B=29-277; PDB; 1NMS
X-ray
1.70 A; A/B=29-277; PDB; 1PAU
X-ray
2.50 A; A=29-175; B=176-277; PDB
1QX3
X-ray; 1.90 A; A=29-277; PDB
1RE1
X-ray; 2.50 A; A=29-175; B=176-277
PDB
1RHJ; X-ray
; 2.20 A; A/C=29-175
B/D=176-277
PDB; 1RHK; X-ray; 2.50 A
A=29-175
B=176-277; PDB; 1RHM; X-ray
2.50 A
A/C=29-175; B/D=176-277; PDB; 1RHQ
X-ray
3.00 A; A/D=29-175; B/E=176-277; PDB
1RHR
X-ray; 3.00 A; A=29-175; B=176-277
PDB
1RHU; X-ray
; 2.51 A; A=29-175
B=176-277
PDB; 2C1E; X-ray; 1.77 A
A=29-175
B=176-277; PDB; 2C2K; X-ray
1.87 A
A=29-175; B=176-277; PDB; 2C2M
X-ray
1.94 A; A=29-175; B=176-277; PDB
2C2O
X-ray; 2.45 A; A=29-175; B=176-277
PDB
2CDR; X-ray
; 1.70 A; A=29-175
B=176-277
PDB; 2CJX; X-ray; 1.70 A
A=29-175
B=176-277; PDB; 2CJY; X-ray
1.67 A
A=29-175; B=176-277; PDB; 2CNK
X-ray
1.75 A; A=29-175; B=176-277; PDB
2CNL
X-ray; 1.67 A; A=29-175; B=176-277
PDB
2CNN; X-ray
; 1.70 A; A=29-175
B=176-277
PDB; 2CNO; X-ray; 1.95 A
A=29-175
B=176-277; PDB; 2DKO; X-ray
1.06 A
A=29-174; B=175-277; PDB; 2H5I
X-ray
1.69 A; A=29-174; B=184-277; PDB
2H5J
X-ray; 2.00 A; A/C=29-174; B/D=184-277
PDB
2H65; X-ray
; 2.30 A; A/C=29-174
B/D=184-277
PDB; 2J30; X-ray; 1.40 A
A=29-277
PDB; 2J31; X-ray; 1.50 A
A=29-277
PDB; 2J32; X-ray; 1.30 A
A=29-277
PDB; 2J33; X-ray; 2.00 A
A=29-277
PDB; 2XYG; X-ray; 1.54 A
A=29-174
B=185-277; PDB; 2XYH; X-ray
1.89 A
A=29-174; B=185-277; PDB; 2XYP
X-ray
1.86 A; A=29-174; B=185-277; PDB
2XZD
X-ray; 2.10 A; A/C=27-175; B/D=176-277
PDB
2XZT; X-ray
; 2.70 A; A/C=29-175
B/D=176-277
PDB; 2Y0B; X-ray; 2.10 A
A/C=29-175
B/D=176-277; PDB; 3DEH; X-ray
2.50 A
A/B/C/D=29-277; PDB; 3DEI; X-ray
2.80 A
A/B/C/D=29-277; PDB; 3DEJ; X-ray
2.60 A
A/B/C/D=29-277; PDB; 3DEK; X-ray
2.40 A
A/B/C/D=29-277; PDB; 3EDQ; X-ray
1.61 A
A/C=29-175; B/D=176-277; PDB; 3GJQ
X-ray
2.60 A; A/C=29-175; B/D=176-277; PDB
3GJR
X-ray; 2.20 A; A/C=29-175; B/D=176-277
PDB
3GJS; X-ray
; 1.90 A; A/C=29-175
B/D=176-277
PDB; 3GJT; X-ray; 2.20 A
A/C=29-175
B/D=176-277; PDB; 3H0E; X-ray
2.00 A
A/B=29-277; PDB; 3ITN; X-ray
1.63 A
A=29-277; PDB; 3KJF; X-ray
2.00 A
A=29-175; B=176-277; PDB; 3PCX
X-ray
1.50 A; A=29-277; PDB; 3PD0
X-ray
2.00 A; A=29-277; PDB; 3PD1
X-ray
1.62 A; A=29-277; PDB; 4DCJ
X-ray
1.70 A; A/D=29-175; B/E=176-277; PDB
4DCO
X-ray; 1.70 A; A/D=29-175; B/E=176-277
PDB
4DCP; X-ray
; 1.70 A; A/D=29-175
B/E=176-277
PDB; 4EHA; X-ray; 1.70 A
A/C=1-277
PDB; 4EHD; X-ray; 1.58 A
A=1-277
PDB; 4EHF; X-ray; 1.66 A
A=1-277
PDB; 4EHH; X-ray; 1.78 A
A=1-277
PDB; 4EHK; X-ray; 1.67 A
A/C=1-277
PDB; 4EHL; X-ray; 1.80 A
A/C=1-277
PDB; 4EHN; X-ray; 1.69 A
A=1-277
PDB; 4JJE; X-ray; 1.48 A
A=29-277
PDB; 4JQY; X-ray; 2.50 A
A/B=34-277
PDB; 4JQZ; X-ray; 2.89 A
A/B=34-277
PDB; 4JR0; X-ray; 1.80 A
A/B=34-277
PDB; 4PRY; X-ray; 1.70 A
A=1-277
PDB; 4PS0; X-ray; 1.63 A
A/B=1-277
PDB; 4QTX; X-ray; 1.97 A
A=1-277
PDB; 4QTY; X-ray; 1.60 A
A=29-277
PDB; 4QU0; X-ray; 1.95 A
A=1-277
PDB; 4QU5; X-ray; 1.91 A
A=1-277
PDB; 4QU8; X-ray; 1.72 A
A=1-277
PDB; 4QU9; X-ray; 1.56 A
A=1-277
PDB; 4QUA; X-ray; 1.89 A
A=1-277
PDB; 4QUB; X-ray; 1.69 A
A=1-277
PDB; 4QUD; X-ray; 2.00 A
A/B=1-277
PDB; 4QUE; X-ray; 1.84 A
A/C=1-277
PDB; 4QUG; X-ray; 1.92 A
A/C=1-277
PDB; 4QUH; X-ray; 1.76 A
A/C=1-277
PDB; 4QUI; X-ray; 1.76 A
A/B=1-277
PDB; 4QUJ; X-ray; 1.50 A
A=1-277
PDB; 4QUL; X-ray; 1.90 A
A/C=1-277
PDB; 5I9B; X-ray; 1.80 A
A=1-277
PDB; 5I9T; X-ray; 1.95 A
A/C=1-277
PDB; 5IAB; X-ray; 1.79 A
A/C=1-277
PDB; 5IAE; X-ray; 1.55 A
A/C=1-277
PDB; 5IAG; X-ray; 1.98 A
A=1-277
PDB; 5IAJ; X-ray; 1.58 A
A=1-277
PDB; 5IAK; X-ray; 1.82 A
A=1-277
PDB; 5IAN; X-ray; 2.70 A
A=1-277
PDB; 5IAR; X-ray; 1.76 A
A=1-277
PDB; 5IAS; X-ray; 1.54 A
A=1-277
PDB; 5IBC; X-ray; 1.66 A
A=1-277
PDB; 5IBP; X-ray; 1.38 A
A=1-277
PDB; 5IBR; X-ray; 1.74 A
A/C=1-277
PDB; 5IC4; X-ray; 2.65 A
A/C/E/G=1-175
B/D/F/H=176-276; PDBsum; 1CP3; -
PDBsum
1GFW; -
; .
PDBsum
1I3O; -
; .
PDBsum
1NME; -
; .
PDBsum
1NMQ; -
; .
PDBsum
1NMS; -
; .
PDBsum
1PAU; -
; .
PDBsum
1QX3; -
; .
PDBsum
1RE1; -
; .
PDBsum
1RHJ; -
; .
PDBsum
1RHK; -
; .
PDBsum
1RHM; -
; .
PDBsum
1RHQ; -
; .
PDBsum
1RHR; -
; .
PDBsum
1RHU; -
; .
PDBsum
2C1E; -
; .
PDBsum
2C2K; -
; .
PDBsum
2C2M; -
; .
PDBsum
2C2O; -
; .
PDBsum
2CDR; -
; .
PDBsum
2CJX; -
; .
PDBsum
2CJY; -
; .
PDBsum
2CNK; -
; .
PDBsum
2CNL; -
; .
PDBsum
2CNN; -
; .
PDBsum
2CNO; -
; .
PDBsum
2DKO; -
; .
PDBsum
2H5I; -
; .
PDBsum
2H5J; -
; .
PDBsum
2H65; -
; .
PDBsum
2J30; -
; .
PDBsum
2J31; -
; .
PDBsum
2J32; -
; .
PDBsum
2J33; -
; .
PDBsum
2XYG; -
; .
PDBsum
2XYH; -
; .
PDBsum
2XYP; -
; .
PDBsum
2XZD; -
; .
PDBsum
2XZT; -
; .
PDBsum
2Y0B; -
; .
PDBsum
3DEH; -
; .
PDBsum
3DEI; -
; .
PDBsum
3DEJ; -
; .
PDBsum
3DEK; -
; .
PDBsum
3EDQ; -
; .
PDBsum
3GJQ; -
; .
PDBsum
3GJR; -
; .
PDBsum
3GJS; -
; .
PDBsum
3GJT; -
; .
PDBsum
3H0E; -
; .
PDBsum
3ITN; -
; .
PDBsum
3KJF; -
; .
PDBsum
3PCX; -
; .
PDBsum
3PD0; -
; .
PDBsum
3PD1; -
; .
PDBsum
4DCJ; -
; .
PDBsum
4DCO; -
; .
PDBsum
4DCP; -
; .
PDBsum
4EHA; -
; .
PDBsum
4EHD; -
; .
PDBsum
4EHF; -
; .
PDBsum
4EHH; -
; .
PDBsum
4EHK; -
; .
PDBsum
4EHL; -
; .
PDBsum
4EHN; -
; .
PDBsum
4JJE; -
; .
PDBsum
4JQY; -
; .
PDBsum
4JQZ; -
; .
PDBsum
4JR0; -
; .
PDBsum
4PRY; -
; .
PDBsum
4PS0; -
; .
PDBsum
4QTX; -
; .
PDBsum
4QTY; -
; .
PDBsum
4QU0; -
; .
PDBsum
4QU5; -
; .
PDBsum
4QU8; -
; .
PDBsum
4QU9; -
; .
PDBsum
4QUA; -
; .
PDBsum
4QUB; -
; .
PDBsum
4QUD; -
; .
PDBsum
4QUE; -
; .
PDBsum
4QUG; -
; .
PDBsum
4QUH; -
; .
PDBsum
4QUI; -
; .
PDBsum
4QUJ; -
; .
PDBsum
4QUL; -
; .
PDBsum
5I9B; -
; .
PDBsum
5I9T; -
; .
PDBsum
5IAB; -
; .
PDBsum
5IAE; -
; .
PDBsum
5IAG; -
; .
PDBsum
5IAJ; -
; .
PDBsum
5IAK; -
; .
PDBsum
5IAN; -
; .
PDBsum
5IAR; -
; .
PDBsum
5IAS; -
; .
PDBsum
5IBC; -
; .
PDBsum
5IBP; -
; .
PDBsum
5IBR; -
; .
PDBsum
5IC4; -
; .
ProteinModelPortal
P42574; -
; .
SMR
P42574; -
; .
BioGrid
107286; 99
; .
DIP
DIP-268N; -
; .
IntAct
P42574; 43
; .
MINT
MINT-147180; -
; .
STRING
9606.ENSP00000311032; -
; .
BindingDB
P42574; -
; .
ChEMBL
CHEMBL2334; -
; .
DrugBank
DB06862; 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
; .
DrugBank
DB08251; 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID
; .
DrugBank
DB03124; 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid
; .
DrugBank
DB08229; [N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID
; .
DrugBank
DB05408; IDN-6556
; .
DrugBank
DB07696; methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate
; .
DrugBank
DB01017; Minocycline
; .
GuidetoPHARMACOLOGY
1619; -
; .
MEROPS
C14.003; -
; .
iPTMnet
P42574; -
; .
PhosphoSitePlus
P42574; -
; .
BioMuta
CASP3; -
; .
DMDM
77416852; -
; .
OGP
P42574; -
; .
EPD
P42574; -
; .
MaxQB
P42574; -
; .
PaxDb
P42574; -
; .
PeptideAtlas
P42574; -
; .
PRIDE
P42574; -
; .
DNASU
836; -
; .
Ensembl
ENST00000308394; ENSP00000311032
; ENSG00000164305; .
Ensembl
ENST00000523916; ENSP00000428929
; ENSG00000164305; .
GeneID
836; -
; .
KEGG
hsa:836; -
; .
UCSC
uc003iwh.3; human
; .
CTD
836; -
; .
DisGeNET
836; -
; .
GeneCards
CASP3; -
; .
HGNC
HGNC:1504; CASP3
; .
HPA
CAB000091; -
; .
HPA
CAB008381; -
; .
HPA
HPA002643; -
; .
MIM
600636; gene
; .
neXtProt
NX_P42574; -
; .
OpenTargets
ENSG00000164305; -
; .
PharmGKB
PA26087; -
; .
eggNOG
KOG3573; Eukaryota
; .
eggNOG
ENOG410ZQIE; LUCA
; .
GeneTree
ENSGT00760000118912; -
; .
HOGENOM
HOG000231878; -
; .
HOVERGEN
HBG050802; -
; .
InParanoid
P42574; -
; .
KO
K02187; -
; .
OMA
DDDMACH; -
; .
OrthoDB
EOG091G05YD; -
; .
PhylomeDB
P42574; -
; .
TreeFam
TF102023; -
; .
BRENDA
3.4.22.56; 2681
; .
Reactome
R-HSA-111459; Activation of caspases through apoptosome-mediated cleavage
; .
Reactome
R-HSA-111463; SMAC binds to IAPs
; .
Reactome
R-HSA-111464; SMAC-mediated dissociation of IAP:caspase complexes
; .
Reactome
R-HSA-111465; Apoptotic cleavage of cellular proteins
; .
Reactome
R-HSA-1474228; Degradation of the extracellular matrix
; .
Reactome
R-HSA-2028269; Signaling by Hippo
; .
Reactome
R-HSA-205025; NADE modulates death signalling
; .
Reactome
R-HSA-211227; Activation of DNA fragmentation factor
; .
Reactome
R-HSA-211736; Stimulation of the cell death response by PAK-2p34
; .
Reactome
R-HSA-264870; Caspase-mediated cleavage of cytoskeletal proteins
; .
Reactome
R-HSA-351906; Apoptotic cleavage of cell adhesion proteins
; .
Reactome
R-HSA-418889; Ligand-independent caspase activation via DCC
; .
Reactome
R-HSA-449147; Signaling by Interleukins
; .
SABIO-RK
P42574; -
; .
SIGNOR
P42574; -
; .
EvolutionaryTrace
P42574; -
; .
GeneWiki
Caspase_3; -
; .
GenomeRNAi
836; -
; .
PMAP-CutDB
P42574; -
; .
PRO
PR:P42574; -
; .
Proteomes
UP000005640; Chromosome 4
; .
Bgee
ENSG00000164305; -
; .
CleanEx
HS_CASP3; -
; .
ExpressionAtlas
P42574; baseline and differential
; .
Genevisible
P42574; HS
; .
GO
GO:0005829; C:cytosol
; IDA:UniProtKB; .
GO
GO:0031264; C:death-inducing signaling complex
; IEA:Ensembl; .
GO
GO:0045121; C:membrane raft
; IEA:Ensembl; .
GO
GO:0005654; C:nucleoplasm
; TAS:Reactome; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0005886; C:plasma membrane
; TAS:Reactome; .
GO
GO:0004190; F:aspartic-type endopeptidase activity
; EXP:Reactome; .
GO
GO:0004861; F:cyclin-dependent protein serine/threonine kinase inhibitor activity
; IEA:Ensembl; .
GO
GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process
; TAS:Reactome; .
GO
GO:0004197; F:cysteine-type endopeptidase activity
; IDA:UniProtKB; .
GO
GO:0097153; F:cysteine-type endopeptidase activity involved in apoptotic process
; IDA:UniProtKB; .
GO
GO:0097200; F:cysteine-type endopeptidase activity involved in execution phase of apoptosis
; IMP:UniProtKB; .
GO
GO:0008233; F:peptidase activity
; IDA:UniProtKB; .
GO
GO:0016005; F:phospholipase A2 activator activity
; IEA:Ensembl; .
GO
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process
; TAS:Reactome; .
GO
GO:0008635; P:activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
; TAS:Reactome; .
GO
GO:0006309; P:apoptotic DNA fragmentation
; TAS:Reactome; .
GO
GO:0006915; P:apoptotic process
; TAS:ProtInc; .
GO
GO:0097190; P:apoptotic signaling pathway
; TAS:BHF-UCL; .
GO
GO:0001782; P:B cell homeostasis
; IEA:Ensembl; .
GO
GO:0045165; P:cell fate commitment
; IEA:Ensembl; .
GO
GO:0006974; P:cellular response to DNA damage stimulus
; IEA:Ensembl; .
GO
GO:0071407; P:cellular response to organic cyclic compound
; IEA:Ensembl; .
GO
GO:0030218; P:erythrocyte differentiation
; IDA:UniProtKB; .
GO
GO:0097194; P:execution phase of apoptosis
; IDA:UniProtKB; .
GO
GO:0097192; P:extrinsic apoptotic signaling pathway in absence of ligand
; TAS:Reactome; .
GO
GO:0034349; P:glial cell apoptotic process
; IEA:Ensembl; .
GO
GO:0007507; P:heart development
; IEA:Ensembl; .
GO
GO:0035329; P:hippo signaling
; TAS:Reactome; .
GO
GO:0021766; P:hippocampus development
; IEA:Ensembl; .
GO
GO:0030216; P:keratinocyte differentiation
; IBA:GO_Central; .
GO
GO:0007611; P:learning or memory
; IEA:Ensembl; .
GO
GO:0046007; P:negative regulation of activated T cell proliferation
; IEA:Ensembl; .
GO
GO:0043066; P:negative regulation of apoptotic process
; IGI:MGI; .
GO
GO:0030889; P:negative regulation of B cell proliferation
; IEA:Ensembl; .
GO
GO:0045736; P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
; IEA:Ensembl; .
GO
GO:0051402; P:neuron apoptotic process
; IEA:Ensembl; .
GO
GO:0030182; P:neuron differentiation
; IBA:GO_Central; .
GO
GO:0048011; P:neurotrophin TRK receptor signaling pathway
; IDA:MGI; .
GO
GO:0030220; P:platelet formation
; TAS:UniProtKB; .
GO
GO:0043525; P:positive regulation of neuron apoptotic process
; IEA:Ensembl; .
GO
GO:0016485; P:protein processing
; IEA:Ensembl; .
GO
GO:0006508; P:proteolysis
; IDA:UniProtKB; .
GO
GO:0016241; P:regulation of macroautophagy
; TAS:ParkinsonsUK-UCL; .
GO
GO:0043200; P:response to amino acid
; IEA:Ensembl; .
GO
GO:0046677; P:response to antibiotic
; IEA:Ensembl; .
GO
GO:0032025; P:response to cobalt ion
; IEA:Ensembl; .
GO
GO:0042493; P:response to drug
; IEA:Ensembl; .
GO
GO:0032355; P:response to estradiol
; IEA:Ensembl; .
GO
GO:0051384; P:response to glucocorticoid
; IEA:Ensembl; .
GO
GO:0009749; P:response to glucose
; IEA:Ensembl; .
GO
GO:0042542; P:response to hydrogen peroxide
; IEA:Ensembl; .
GO
GO:0001666; P:response to hypoxia
; IEA:Ensembl; .
GO
GO:0032496; P:response to lipopolysaccharide
; IEA:Ensembl; .
GO
GO:0035094; P:response to nicotine
; IEA:Ensembl; .
GO
GO:0034612; P:response to tumor necrosis factor
; TAS:BHF-UCL; .
GO
GO:0009411; P:response to UV
; IEA:Ensembl; .
GO
GO:0010165; P:response to X-ray
; IEA:Ensembl; .
GO
GO:0007605; P:sensory perception of sound
; IEA:Ensembl; .
GO
GO:0043029; P:T cell homeostasis
; IEA:Ensembl; .
GO
GO:0042060; P:wound healing
; IEA:Ensembl; .
CDD
cd00032; CASc
; 1; .
Gene3D
3.40.50.1460; -
; 1; .
InterPro
IPR029030; Caspase-like_dom
; .
InterPro
IPR015470; Caspase_3
; .
InterPro
IPR033139; Caspase_cys_AS
; .
InterPro
IPR016129; Caspase_his_AS
; .
InterPro
IPR002138; Pept_C14_p10
; .
InterPro
IPR001309; Pept_C14_p20
; .
InterPro
IPR015917; Pept_C14A
; .
PANTHER
PTHR10454:SF178; PTHR10454:SF178
; 1; .
PRINTS
PR00376; IL1BCENZYME
; .
SMART
SM00115; CASc
; 1; .
SUPFAM
SSF52129; SSF52129
; 1; .
PROSITE
PS01122; CASPASE_CYS
; 1; .
PROSITE
PS01121; CASPASE_HIS
; 1; .
PROSITE
PS50207; CASPASE_P10
; 1; .
PROSITE
PS50208; CASPASE_P20
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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